- TitleLetter from William Grey Walter to E.D. Adrian, 8 October 1942
- ReferenceBURD/A/09/05
- Production date08-10-1942 - 08-10-1942
- Walter, William GreyBiographyBiography(1910-1977), neurophysiologist William Grey Walter (also known as Grey Walter) was born in Kansas City, Missouri, on 19 February 1910 to journalist parents Karl Wilhelm Walter (1880-1965) and Minerva (Margaret) Lucrezia Hardy (1879-1953). The Walter family moved from the United States to Britain in 1915, where William remained for the rest of his life. He was educated at Westminster School (1922-1928), before taking the Natural Science Tripos at King’s College, Cambridge (1928-1931). He went on to pursue postgraduate research on nerve physiology and conditioned reflexes, gaining his MA in 1935. After completing his MA, Walter was invited to work at the Central Pathological Laboratory of the Maudsley Hospital, London, under neuropsychiatrist Frederick Lucien Golla (1877-1968). Since the late 1920s, Golla had become increasingly interested in the clinical applications of the burgeoning field of electroencephalography (EEG), the measurement of the electrical activity of the brain via electrodes placed on the scalp. Noting his skill in technical matters, Golla encouraged Walter to develop increasingly sophisticated EEG devices, and supported his application for a Rockefeller Travelling Fellowship to visit the Jena laboratory of German physiologist Hans Berger (1873-1941), widely credited as the founder of electroencephalography. Walter went on to achieve several key ‘firsts’ in electroencephalography, including the first detection of a cerebral tumour using the technique in 1936. Between 1936 and 1939, Walter expanded his research programme and took readings from hundreds of patients, focusing particularly on the electrical patterns of epilepsy. In 1939, Golla was invited to become director of the new Burden Neurological Institute, Bristol, an independent research unit specialising in the investigation and treatment of neurological, psychological, and psychiatric disorders, and invited Walter to become director of the Institute’s Physiology Department. At the Burden, Walter further developed his EEG apparatus, developing the automatic frequency analyser and the toposcope in 1943 and 1950 respectively. His research programme also became increasingly ambitious, with investigations into the cerebral effects of stroboscopic light beginning in 1947 and, later, the discovery of ‘contingent negative variation’ (CNV, or the ‘expectancy wave’) in the 1960s. Walter also played a key role in the professionalization of electroencephalography during this period, co-founding the journal Electroencephalography and Clinical Neurophysiology and organising meetings of the EEG Society (1943-1989). Outside of his clinical work, Walter became a key figure in early British cybernetics, the study of feedback, control, and communication systems in humans and machines that synthesised approaches from engineering, biology, and mathematics. He co-founded the Ratio Club, an informal dining and discussion group which provided a key social outlet for cybernetic enthusiasts, which met between 1949 and 1955. He also built several cybernetic devices in his spare time, the most famous of which were his robotic tortoises, or Machina Speculatrix, designed to function as simple models of the adaptable human brain. These received national attention when they were exhibited on television in 1950 and at the Festival of Britain in 1951. He also became a prolific public intellectual, writing 170 scientific publications, serving as an expert witness in court courses, appearing frequently on the BBC, and writing an immensely popular non-specialist text on his neuroscientific work, The Living Brain (1953). His work also gained a surprising popularity among counter-cultural artists during the 1950s and 1960s, including Beat writers William S. Burroughs and Allen Ginsberg, who saw Walter’s research as part of a broader investigation of human consciousness. Walter was married twice, first to Katharine Monica Ratcliffe in 1934 and then to Vivian Joan Dovey (1915-1980) in 1947, with whom he had one son, Timothy Walter (1949-1976). Walter and Dovey separated in 1960 and divorced in 1973. After their separation, Walter lived with Lorraine Josephine Aldridge (née Donn) until 1972. In 1970, Walter suffered severe brain damage following a road accident, forcing him to retire from full-time research work. He died of a heart attack in 1977.
- Scope and ContentDiscusses his Medical Research Council (MRC) grant to develop a portable two channel E.E.G. machine, and its possible future manufacture by Marconi. Mentions a meeting held with E.A. Carmichael, George Dawson, Denis Hill, and Denis Williams to try to pressure the government into sponsoring E.E.G. manufacture and the creation of a national network of E.E.G. centres.
- Extent1 xerox letter, 3 pages
- LanguageEnglish
- Level of descriptionITEM
- Repository nameScience Museum, London
- Adrian, Edgar DouglasBiographyBiography(1889-1977) 1st Baron Adrian, physiologist Edgar Douglas Adrian was born in London on 30 November 1889 to parents Alfred Douglas Adrian and Flora Lavinia Barton. He was educated at Westminster School before taking the Natural Sciences Tripos at Trinity College, Cambridge. His research on the nerve impulse with his supervisor, physiologist Keith Lucas (1879-1916), won him a fellowship at Trinity College in 1913. During the First World War, Adrian abandoned research to complete a medical degree at St. Bartholomew’s Hospital, London, and he subsequently worked on nerve injuries and shell shock at the National Hospital for Nervous Diseases, Queen Square and Connaught Military Hospital, Aldershot. In 1919, he returned to his research at Cambridge and conducted several pioneering studies in electrophysiology and neurology. In the 1930s, Adrian became increasingly interested in the electrical rhythms of the nervous system and wrote several foundational papers in the burgeoning field of electroencephalography (the measurement of the electrical activity of the brain), including a 1934 paper with B.H.C. Matthews (1906-1986) which confirmed the findings of German physiologist and EEG founder Hans Berger (1873-1941). His research agenda expanded during the Second World War, with investigations into balance, spatial orientation, touch, pain, and smell. Adrian became Professor of Physiology at Cambridge in 1937 and master of Trinity College in 1951, and occupied a number of prestigious positions in universities and societies in the following decades, including President of the Royal Society (1950-1955) and the Royal Society of Medicine (1960-1961), and Chancellor of the University of Leicester (1957-1971) and the University of Cambridge (1968-1975), as well as taking part in a number of cross-benches on academic, medical, and scientific issues in the House of Lords. Adrian married Hester Agnes Pinsent (1899-1966) in 1923, with whom he had three children. He died in Cambridge on 4 August 1977.
- Medical Research CouncilBiographyBiographyThe Medical Research Council (MRC), formerly the Medical Research Committee, is a government-sponsored national funding body for medical research in Britain. The Medical Research Committee was established on 20 June 1913 as an independent body responsible for the organisation of state-funded medical research. The financial support for this work was provided by a subsection of the 1911 National Insurance Act, which set aside £57,000 a year for research purposes. Although initially earmarked for combatting tuberculosis (TB), the Committee was given the freedom to pursue a much broader set of investigations into health and disease. In 1914, Cambridge physiologist Walter Morley Fletcher (1873-1933) was appointed the first Secretary of the Committee. In the same year, work began on the construction of a central research institute for the Committee in Hampstead, London, which opened as the National Institute for Medical Research (NIMR) in 1920. After the First World War, the Committee was implicated in larger-scale debates about the reorganisation of government and public services. The Machinery of Government Committee, also known as the Haldane Committee, determined that the Medical Research Committee should remain independent of departmental oversight and separate from the recently established Ministry of Health. This decision was confirmed by the granting of a Royal Charter to the newly-christened Medical Research Council on 20 March 1920. The Charter freed the MRC from its original financial provisions under the 1911 Act and instead provided direct parliamentary funding at the discretion of the Committee of Privy Council for Medical Research. In practice, the Privy Council exerted little influence on the day-to-day running of the MRC, with research priorities and staff appointments largely made in-house. While the Second World War (1939-1945) and the foundation of the National Health Service (NHS) in 1948 encouraged closer collaboration between the MRC and government departments, the Council’s autonomy remained largely intact throughout the twentieth-century. Following the 1965 Science and Technology Act and the subsequent abolition of the Privy Council, funding authority over the MRC passed to the Secretary of State for Education and Science. Following a series of departmental closures and mergers in the 1990s, 2000s, and 2010s, financial responsibility for the MRC has been held by the Department for Business, Energy and Industrial Strategy since 2016.
- Marconi Instruments LtdBiographyBiographyMarconi Instruments Limited was a British manufacturer of electronic test and measurement equipment, based in St Albans and Stevenage, England. The company was formed following the Marconi Company buy-out of Marconi-Ecko Instruments in 1941 and was sold to IFR Systems Inc. in 1998. The company was named after Italian inventor Guglielmo Marconi (1874-1937), a pioneer in radio and telegraphy who founded the Wireless Telegraph and Signal Company (later the Marconi Company) in 1897.
- Carmichael, Edward ArnoldBiographyBiography(1896-1978), neurologist Edward Arnold Carmichael was born in Edinburgh on 25 March 1896. He was educated at Edinburgh Academy before serving in the military during the First World War (1914-1918). On his return, he pursued a medical degree at the Edinburgh Royal Infirmary, qualifying in 1921. After a number of junior medical and surgical posts in Edinburgh, Carmichael decided to specialise in neurology and took up the post of medical officer at the National Hospital for Nervous Diseases in Queen Square, London, in 1923. After his residency, Carmichael became a registrar in neurology at St Bartholomew’s Hospital, London, before returning to Queen Square as honorary assistant physician. He was soon promoted to Director of the Medical Research Council’s Neurological Research Unit at the hospital, where he remained until his retirement in 1961. After his retirement, Carmichael moved to the United States to pursue full-time research and teaching. He was elected an honorary alumnus of the Neurological Institute of New York in 1966. Carmichael died on 9 February 1978.
- Dawson, George DuncanBiographyBiography(1912-1983), physiologist George Duncan Dawson was born in Manchester in 1912. He gained his MSc for research on nerve action potentials in 1933, before qualifying in medicine at Manchester Medical School in 1936. Well known for his skills in electrical engineering, Dawson secured a research appointment at the Manchester Royal Infirmary in 1938 and helped to set up the electroencephalography (EEG, the measurement of the electrical activity of the brain) laboratory of neurologist Sir Geoffrey Jefferson (1886-1961). During the Second World War, Dawson joined the Royal Air Force but was invalided out in 1941 after contracting tuberculosis. While recovering, he embarked upon a series of EEG field tests at the David Lewis Colony in Sandlebridge, Cheshire, studying the electrical brain activity of patients with epilepsy. Attending the early wartime meetings of the EEG Society (1942-1989), Dawson formed collaborative relationships with several prominent EEG enthusiasts, including neurophysiologist William Grey Walter (1910-1977) and psychiatrist Denis Hill (1913-1982). In 1944, Dawson was invited to join the Medical Research Council unit at the National Hospital for Nervous Diseases, Queen Square under neurologist E.A. Carmichael (1896-1978). There he developed techniques for identifying small electroencephalographic signals against background noise while studying patients with epilepsy. The technique has since been celebrated as the foundation of modern conduction velocity studies (the study of the speed of electrical impulses in the human nervous system). In 1961, Dawson became head of the Department of Clinical Neurophysiology at the Institute of Psychiatry, London. In 1966, he was appointed Second Professor of Physiology at University College London, where he remained until his retirement. In retirement, he continued research into epilepsy, developing computer-based methods for assessing drug treatments at Lingfield Epileptic Colony. Dawson was married to biochemist and electroencephalographer Mollie Heppenstall, with whom he had two sons. He died on 13 November 1983.
- Hill, John Denis NelsonBiographyBiography(1913-1982), Knight, psychiatrist Sir John Denis Nelson Hill was born in Orleton, Herefordshire on 5 October 1913. He was educated at Shewsbury School before pursuing a medical degree at St Thomas’s Hospital, London, qualifying in 1936. Interested in specialising in psychiatry, Hill then went to Maida Vale Hospital, London, to study neurology under Walter Russell Brain (1895-1966). While working at Maida Vale, Hill met neurophysiologist William Grey Walter (1910-1977), who first stoked Hill’s interest in the field of electroencephalography (EEG, the measurement of the electrical activity of the brain). In 1938, Hill returned to St Thomas’s to take up an assistant position within the Department of Psychiatry. Following the outbreak of the Second World War (1939-1945) a year later, Hill moved to work at the Emergency Hospital in Belmont, Surrey, where he set up an EEG laboratory to study various neurological and psychiatric conditions, including epilepsy. This work led to a collaboration with neurosurgeon Murray Falconer (1910-1977) on the development of the temporal lobectomy (the surgical removal of the temporal lobe) as a treatment for temporal lobe epilepsy. After the war, Hill was invited to set up an EEG laboratory at the Maudsley Hospital’s new Institute of Psychiatry. This was closely followed by his appointment as Lecturer in Psychological Medicine at King’s College Hospital in 1947. During the post-war period, Hill further established his reputation as an expert on the psychiatric dimensions of electroencephalography, serving on a number of committees investigating the technique’s use on patients, prisoners, and juvenile offenders. In 1966, Hill returned to the Institute of Psychiatry to become Professor of Psychiatry, a post which he retained until his retirement in 1979. Hill was married twice, first to Phoebe Elizabeth Herschel in 1938, and then to Lorna Wheelan in 1962. He had four children. Hill died following a heart attack on 5 May 1982.
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- Finding aidsBox 2 - BURD A6/60 - A15; B
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- contains 5 partsTOPBURD Papers relating to the clinical and experimental neuroscientific work carried out at the Burden Neurological Institute
- contains 16 partsSERIESBURD/A Main papers
- contains 31 partsSUB-SERIESBURD/A/09 Correspondence with E.D. Adrian